The Opportunity:
We are seeking a self-motivated researcher who is excited to join a dynamic and collaborative team of scientists driving the discovery of novel small molecule therapeutics in oncology and genetic disease. In this role, you will design and execute molecular and cell biology experiments focused on evaluation of candidate molecules, and development of novel biomarkers. You will interact and collaborate cross-functionally with scientists in other departments, including biochemists, chemists, and computational and structural biologists while growing your understanding of drug discovery and helping bring medicines to patients.
Your Role:
- Design and perform cell and molecular biology experiments to support the biological evaluation of small molecules impacting biological targets
- Optimize and conduct weekly cell-based assays to enable medicinal chemistry efforts and structure activity relationship assessment
- Develop and perform target engagement and pharmacodynamic assays from cells and/or in vivo samples
- Maintain good written records of laboratory procedures, results and conclusions
- Analyze data carefully and report findings to the team
- Collaborate with CROs for any outsourcing needs and integrate data analysis
- Present your work at regular department and company meetings
Your Background:
- MS/BS, 2-5 years of industry experience in drug development
- Exceptional tissue and cell culture skills
- Experience designing, executing and troubleshooting high throughput screens
- Adept at nucleic acid purification, DNA cloning, qPCR, Western blotting, reporter transcriptional assays, immunoprecipitation, ELISAs, si/shRNA, CRISPR, lentiviral gene knockdown, imaging
- Ability to design and execute experiments, analyze and document results
- Excellent organizational and communication skills
- Excellent problem-solving skills and ability to multi-task
Estimated Salary Range: [ $72,000 - $102,000].
The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.
#BP1
About Relay Therapeutics
Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process.
Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you’re excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!
