Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).

Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine's toughest problems, we encourage you to read the opportunity below and apply.

The Opportunity

The Senior Director, Marketing Excellence, will play a pivotal role in shaping Amylyx's commercial strategy and driving seamless, integrated engagement across all customer touchpoints. This leader will be responsible for designing and executing a comprehensive, enterprise-wide omnichannel vision that connects with healthcare professionals and community members (patients and caregivers) through personalized, high-impact experiences. This role will integrate digital and traditional channels, leverage data-driven insights, and collaborate across functions to ensure alignment with brand objectives and launch plans. As a key strategic leader, you will shape how Amylyx engages customers, driving innovation and measurable impact. This role will also lead Marketing Operations with a focus on excellence across all aspects of Marketing.

This is a unique opportunity for a strategic, forward-thinking marketer to define how Amylyx leverages technology, analytics, and creative storytelling to deliver consistent, high-value engagement. By combining strategic insight with flawless execution, this individual will help position Amylyx as a leader in omnichannel excellence within the life sciences industry.

Responsibilities

Lead the enterprise-wide digital and omnichannel vision for Amylyx, establishing the standards, principles, and operating model that guide customer engagement across all channels.
Develop and execute an integrated omnichannel marketing capability and strategy aligned with brand objectives and launch timelines, supported by a robust digital customer engagement capability roadmap.
Define and optimize end-to-end customer journeys for HCPs and community members to ensure personalized, consistent experiences across personal and nonpersonal touchpoints, overseeing campaign execution across CRM, marketing automation platforms, and third-party media.
Partner with brand teams to advise on the creation of compelling, compliant, audience-appropriate content while ensuring alignment with regulatory requirements.
Collaborate cross functionally with Commercial, Medical Affairs, and Corporate Communications to ensure seamless integration and synergy across all customer-facing activities.
Establish measurement frameworks with KPIs and dashboards to monitor engagement, conversion, and ROI, partnering closely with IT and analytics teams to ensure the data infrastructure supports real-time optimization.
Drive continuous improvement by leveraging data driven insights to evolve strategy, enhance performance, and identify new opportunities for customer impact.
Oversee governance, optimization, and administration of marketing CRM, marketing automation, analytics platforms, asset management systems, and related martech tools.
Oversee congress operations, material distribution, inventory, print/fulfillment, and speaker bureau operations and related budgets.
Develop procedures, documentation, and training to ensure compliant, efficient, and repeatable execution across Marketing.

Requirements

Bachelor's degree, MBA or advanced degree preferred
10+ years of marketing experience, with at least 5 years in omnichannel or digital marketing leadership roles within biotech/pharma
Proven track record of developing and executing integrated marketing strategies for product launches
Deep understanding of regulatory and compliance requirements in the life sciences industry
Strong analytical skills and experience with marketing technology platforms (CRM, automation, analytics)
Exceptional leadership, communication, and project management skills

Work Location and Conditions

At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations candidates must be able to attend meetings at our office in Cambridge, MA on a regular basis. Preference will be given to candidates who reside in the New England region and can be in person on an as needed basis.
When working remotely, you must have access to a work setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.

Compensation

The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate's experience, skills, and qualifications, as well as considerations of internal equity.

Estimated Pay Range

$239,000—$269,000 USD

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Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx's management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Amylyx Pharmaceuticals

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Senior Director, Marketing Excellence